Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer.

Histone modifications are key regulators of chromatin function. However, little is known to what extent histone modifications can directly impact on chromatin. Here, we address how a modification within the globular domain of histones regulates chromatin function. We demonstrate that H3K122ac can be...

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Bibliographic Details
Main Authors: Tropberger, P, Pott, S, Keller, C, Kamieniarz-Gdula, K, Caron, M, Richter, F, Li, G, Mittler, G, Liu, E, Bühler, M, Margueron, R, Schneider, R
Format: Journal article
Language:English
Published: 2013