Interferon regulatory factor 5 controls necrotic core formation in atherosclerotic lesions by impairing efferocytosis.

<h4>Background</h4> <p>Myeloid cells are central to atherosclerotic lesion development and vulnerable plaque formation. Impaired ability of arterial phagocytes to uptake apoptotic cells (efferocytosis), promotes lesion growth and establishment of a necrotic core. The transcription...

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Main Authors: Seneviratne, C, Edsfeldt, A, Cole, J, Kassiteridi, C, Swart, M, Park, I, Green, P, Khoyratty, T, Saliba, D, Goddard, M, Sansom, S, Goncalves, I, Krams, R, Udalova, I, Monaco, C
Format: Journal article
Language:English
Published: American Heart Association 2017