Interferon regulatory factor 5 controls necrotic core formation in atherosclerotic lesions by impairing efferocytosis.
<h4>Background</h4> <p>Myeloid cells are central to atherosclerotic lesion development and vulnerable plaque formation. Impaired ability of arterial phagocytes to uptake apoptotic cells (efferocytosis), promotes lesion growth and establishment of a necrotic core. The transcription...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Heart Association
2017
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