Use of cell-penetrating-peptides in oligonucleotide splice switching therapy.

The hydrophobic plasma membrane constitutes an indispensable barrier for cells, allowing influx of essential molecules while preventing access to other macromolecules. Although pivotal for the maintenance of cells, the inability to cross the plasma membrane is one of the major obstacles toward curre...

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Autors principals: El Andaloussi, SA, Hammond, S, Mäger, I, Wood, M
Format: Journal article
Idioma:English
Publicat: 2012