Use of cell-penetrating-peptides in oligonucleotide splice switching therapy.

The hydrophobic plasma membrane constitutes an indispensable barrier for cells, allowing influx of essential molecules while preventing access to other macromolecules. Although pivotal for the maintenance of cells, the inability to cross the plasma membrane is one of the major obstacles toward curre...

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Main Authors: El Andaloussi, SA, Hammond, S, Mäger, I, Wood, M
格式: Journal article
语言:English
出版: 2012