Infectious delivery of 120-kilobase genomic DNA by an epstein-barr virus amplicon vector.
It has been shown in a wide variety of contexts that persistent gene expression can best be obtained by using the genomic locus of a transgene. However, the size of most genomic loci precludes their use in current viral gene therapy vectors. Large transgene capacity and extrachromosomal persistence...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2002
|