A disease-associated mutation in fibrillin-1 differentially regulates integrin-mediated cell adhesion

Fibrillins serve as scaffolds for the assembly of elastic fibers that contribute to the maintenance of tissue homeostasis and regulate growth factor signaling in the extracellular space. Fibrillin-1 is a modular glycoprotein that includes 7 latent transforming growth factor β (TGFβ)-binding protein-...

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Bibliographic Details
Main Authors: Del Cid, JS, Reed, NI, Molnar, K, Liu, S, Dang, B, Jensen, SA, DeGrado, W, Handford, PA, Sheppard, D, Sundaram, AB
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2019