Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.

Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization.

Members of the p53 tumor suppressor family are expressed as multiple isoforms. Isoforms having an N-terminal transactivation domain are transcriptionally active while those ones lacking this domain often inhibit the transcriptional activity of other family members. In squamous cell carc...

Bibliografski detalji
Glavni autori:	Gebel, J, Luh, L, Coutandin, D, Osterburg, C, Löhr, F, Schäfer, B, Frombach, A, Sumyk, M, Buchner, L, Krojer, T, Salah, E, Mathea, S, Güntert, P, Knapp, S, Dötsch, V
Format:	Journal article
Jezik:	English
Izdano:	Nature Publishing Group 2016

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