Structural and functional analysis of serine-ADP-ribosylation

<p>ADP-ribosylation is a protein post-translational modification involved in several biological pathways, including the DNA damage response. PARP1, one of the primary sensors of DNA breaks, and the main enzyme responsible for ADP-ribosylation has been the subject of study for several years. De...

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Bibliographic Details
Main Author: Fontana, P
Other Authors: Ahel, I
Format: Thesis
Language:English
Published: 2018