Randomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1

<strong>Background</strong> The failure of DNA vaccination in humans, in contrast to its efficacy in some species, is unexplained. Observational and interventional experimental evidence suggests that DNA immunogenicity may be prevented by binding of human serum amyloid P component (SAP)....

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Bibliographic Details
Main Authors: Borthwick, N, Lane, T, Moyo, N, Crook, A, Shim, J, Baines, I, Wee, E, Hawkins, P, Gillmore, J, Hanke, T, Pepys, M
Format: Journal article
Language:English
Published: Public Library of Science 2018