T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation.
T cell activation by nonself peptide-major histocompatibility complex (MHC) antigenic complexes can be blocked by particular sequence variants in a process termed T cell receptor antagonism. The inhibition mechanism is not understood, although such variants are encountered in viral infections and ma...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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