T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation.

T cell activation by nonself peptide-major histocompatibility complex (MHC) antigenic complexes can be blocked by particular sequence variants in a process termed T cell receptor antagonism. The inhibition mechanism is not understood, although such variants are encountered in viral infections and ma...

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Váldodahkkit: Sumen, C, Dustin, M, Davis, M
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2004