NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma.

NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma.

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BACKGROUND: Both oxaliplatin/capecitabine-based chemoradiation (OXCAP-RT) and carboplatin-paclitaxel based radiation (CarPac-RT) are active regimens in oesophageal adenocarcinoma, but no randomised study has compared their efficacy and toxicity. This randomised phase II "pick a winner" tri...

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Bibliographic Details
Main Authors: Mukherjee, S, Hurt, C, Gwynne, S, Bateman, A, Gollins, S, Radhakrishna, G, Hawkins, M, Canham, J, Lewis, W, Grabsch, H, Sharma, R, Wade, W, Maggs, R, Tranter, B, Roberts, A, Sebag-Montefiore, D, Maughan, T, Griffiths, G, Crosby, T
Format: Journal article
Language:English
Published: 2015

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