A polymorphism in Toll-interleukin 1 receptor domain containing adaptor protein is associated with susceptibility to meningeal tuberculosis.

BACKGROUND: Although meningitis is the most severe form of infection caused by Mycobacterium tuberculosis, the immunopathogenesis of this disease is poorly understood. We tested the hypothesis that polymorphisms in Toll-interleukin 1 receptor domain containing adaptor protein (TIRAP), an adaptor pr...

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Bibliographic Details
Main Authors: Hawn, T, Dunstan, S, Thwaites, G, Simmons, C, Thuong, N, Lan, N, Quy, H, Chau, T, Hieu, N, Rodrigues, S, Janer, M, Zhao, L, Hien, T, Farrar, J, Aderem, A
Format: Journal article
Language:English
Published: 2006