CpG island chromatin: a platform for gene regulation.

The majority of mammalian gene promoters are encompassed within regions of the genome called CpG islands that have an elevated level of non-methylated CpG dinucleotides. Despite over 20 years of study, the precise mechanisms by which CpG islands contribute to regulatory element function remain poorl...

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Bibliographic Details
Main Authors: Blackledge, N, Klose, R
Format: Journal article
Language:English
Published: 2011