CpG island chromatin: a platform for gene regulation.
The majority of mammalian gene promoters are encompassed within regions of the genome called CpG islands that have an elevated level of non-methylated CpG dinucleotides. Despite over 20 years of study, the precise mechanisms by which CpG islands contribute to regulatory element function remain poorl...
Main Authors: | Blackledge, N, Klose, R |
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Format: | Journal article |
Language: | English |
Published: |
2011
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