Novel aspects of the molecular mechanisms controlling insulin secretion.

Pancreatic beta-cells secrete insulin by Ca(2+)-dependent exocytosis of secretory granules. beta-cell exocytosis involves SNARE (soluble NSF-attachment protein receptor) proteins similar to those controlling neurotransmitter release and depends on the close association of L-type Ca(2+) channels and...

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Detalles Bibliográficos
Main Authors: Eliasson, L, Abdulkader, F, Braun, M, Galvanovskis, J, Hoppa, M, Rorsman, P
Formato: Journal article
Idioma:English
Publicado: 2008