Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.
We demonstrate that distinct forms of the yeast chromatin-remodeling enzyme Isw1p sequentially regulate each stage of the transcription cycle. The Isw1a complex (Iswlp/Ioc3p) represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome, whereas the Isw1b c...
| Главные авторы: | , , , , , |
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| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
2003
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