Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

We demonstrate that distinct forms of the yeast chromatin-remodeling enzyme Isw1p sequentially regulate each stage of the transcription cycle. The Isw1a complex (Iswlp/Ioc3p) represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome, whereas the Isw1b c...

Full description

Bibliographic Details
Main Authors:	Morillon, A, Karabetsou, N, O'Sullivan, J, Kent, N, Proudfoot, N, Mellor, J
Format:	Journal article
Language:	English
Published:	2003

Similar Items

In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p.
by: Kent, N, et al.
Published: (2001)

Methylation of histone H3 K4 mediates association of the Isw1p ATPase with chromatin.
by: Santos-Rosa, H, et al.
Published: (2003)

The Isw2 chromatin-remodeling ATPase cooperates with the Fkh2 transcription factor to repress transcription of the B-type cyclin gene CLB2.
by: Sherriff, J, et al.
Published: (2007)

A role for chromatin remodeling in transcriptional termination by RNA polymerase II.
by: Alén, C, et al.
Published: (2002)

Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast.
by: Morillon, A, et al.
Published: (2003)

Nucleosome remodeling and transcriptional repression are distinct functions of Isw1 in Saccharomyces cerevisiae.
by: Pinskaya, M, et al.
Published: (2009)

The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism
by: Timothy J Parnell, et al.
Published: (2015-03-01)

Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex.
by: Moreau, J, et al.
Published: (2003)

The chromatin remodeler ISW1 is a quality control factor that surveys nuclear mRNP biogenesis
by: Babour, A, et al.
Published: (2016)

Dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers
by: Jee Min Kim, et al.
Published: (2024-03-01)

Gene loops juxtapose promoters and terminators in yeast.
by: O'Sullivan, J, et al.
Published: (2004)

The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling.
by: Bitoun, E, et al.
Published: (2007)

Interplay between acetylation and ubiquitination of imitation switch chromatin remodeler Isw1 confers multidrug resistance in Cryptococcus neoformans
by: Yang Meng, et al.
Published: (2024-01-01)

Cbf1p is required for chromatin remodeling at promoter-proximal CACGTG motifs in yeast.
by: Kent, N, et al.
Published: (2004)

Cbf1p modulates chromatin structure, transcription and repair at the Saccharomyces cerevisiae MET16 locus.
by: Ferreiro, J, et al.
Published: (2004)

The dynamics of chromatin remodeling at promoters.
by: Mellor, J
Published: (2005)

Dynamic lysine methylation on histone H3 defines the regulatory phase of gene transcription.
by: Morillon, A, et al.
Published: (2005)

Histone Octamer Structure Is Altered Early in ISW2 ATP-Dependent Nucleosome Remodeling
by: Arjan Hada, et al.
Published: (2019-07-01)

Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast.
by: Mischo, H, et al.
Published: (2013)

The PHD and chromo domains regulate the atpase activity of the human chromatin remodeler CHD4
by: Watson, A, et al.
Published: (2012)

The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4.
by: Watson, A, et al.
Published: (2012)

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II.
by: Dye, M, et al.
Published: (2001)

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II.
by: Dye, M, et al.
Published: (1999)

How RNA polymerase II terminates transcription in higher eukaryotes.
by: Proudfoot, N
Published: (1989)

Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut.
by: Proudfoot, N
Published: (2016)

High altitude termination. Regulation of Transcription Elongation and Termination: a Keystone Symposium, Keystone, CO, USA, April 19-25, 1991.
by: Proudfoot, N
Published: (1991)

DNA elongation by the human DNA polymerase lambda polymerase and terminal transferase activities are differentially coordinated by proliferating cell nuclear antigen and replication protein A.
by: Maga, G, et al.
Published: (2005)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
by: Gromak, N, et al.
Published: (2006)

Molecular dissection of mammalian RNA polymerase II transcriptional termination.
by: West, S, et al.
Published: (2008)

Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin
by: Jee Min Kim, et al.
Published: (2021-07-01)

Chromatin remodeling in oligodendrogenesis
by: E. V. Antontseva, et al.
Published: (2021-09-01)

Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4
by: Morra, R, et al.
Published: (2012)

Concerted action of the PHD, chromo and motor domains regulates the human chromatin remodelling ATPase CHD4.
by: Morra, R, et al.
Published: (2012)

Transcriptional termination signals for RNA polymerase II in fission yeast.
by: Birse, C, et al.
Published: (1997)

A pause site for RNA polymerase II is associated with termination of transcription.
by: Enriquez-Harris, P, et al.
Published: (1991)

Defining the Influence of the A12.2 Subunit on Transcription Elongation and Termination by RNA Polymerase I In Vivo
by: Andrew M. Clarke, et al.
Published: (2021-11-01)

CDK12 globally stimulates RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation
by: Tellier, M, et al.
Published: (2020)

RBM22 regulates RNA polymerase II 5′ pausing, elongation rate, and termination by coordinating 7SK-P-TEFb complex and SPT5
by: Xian Du, et al.
Published: (2024-04-01)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination
by: West, S, et al.
Published: (2008)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.
by: West, S, et al.
Published: (2008)