Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

We demonstrate that distinct forms of the yeast chromatin-remodeling enzyme Isw1p sequentially regulate each stage of the transcription cycle. The Isw1a complex (Iswlp/Ioc3p) represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome, whereas the Isw1b c...

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Hlavní autoři: Morillon, A, Karabetsou, N, O'Sullivan, J, Kent, N, Proudfoot, N, Mellor, J
Médium: Journal article
Jazyk:English
Vydáno: 2003