Anticancer imidazoacridinone C-1311 is effective in androgen-dependent and androgen-independent prostate cancer cells

The androgen receptor (AR) plays a critical role in prostate cancer (PCa) development and metastasis. Thus, blocking AR activity and its downstream signaling constitutes a major strategy for PCa treatment. Here, we report on the potent anti-PCa activity of a small-molecule imidazoacridinone, C-1311....

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Bibliographic Details
Main Authors: Niemira, M, Borowa-Mazgaj, B, Bader, SB, Moszyńska, A, Ratajewski, M, Karaś, K, Kwaśniewski, M, Krętowski, A, Mazerska, Z, Hammond, EM, Skwarska, A
Format: Journal article
Language:English
Published: MDPI 2020