Structure determination of noncanonical RNA motifs guided by ¹H NMR chemical shifts.
Structured noncoding RNAs underlie fundamental cellular processes, but determining their three-dimensional structures remains challenging. We demonstrate that integrating ¹H NMR chemical shift data with Rosetta de novo modeling can be used to consistently determine high-resolution RNA structures. On...
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Bibliographic Details
| Main Authors: |
Sripakdeevong, P,
Cevec, M,
Chang, A,
Erat, M,
Ziegeler, M,
Zhao, Q,
Fox, G,
Gao, X,
Kennedy, S,
Kierzek, R,
Nikonowicz, E,
Schwalbe, H,
Sigel, R,
Turner, D,
Das, R |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2014
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