Rab GEFs and GAPs.

Rab GEFs and GAPs.

Rabs are GTP-binding proteins with conserved functions in membrane trafficking. They are regulated by a diverse group of structurally unrelated GDP-GTP exchange factors (GEFs), and a family of GTP-hydrolysis activating proteins (GAPs) containing the conserved TBC domain. Recent structural and cell b...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Barr, F, Lambright, D
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2010

Eitemau Tebyg

Rab regulation by GEFs and GAPs during membrane traffic
gan: Lamber, E, et al.
Cyhoeddwyd: (2019)

Rab18 and a Rab18 GEF complex are required for normal ER structure.
gan: Gerondopoulos, A, et al.
Cyhoeddwyd: (2014)

RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
gan: Nottingham, R, et al.
Cyhoeddwyd: (2011)

Planar cell polarity effector proteins inturned and fuzzy form a Rab23 GEF complex
gan: Gerondopoulos, A, et al.
Cyhoeddwyd: (2019)

RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.
gan: Nottingham, R, et al.
Cyhoeddwyd: (2012)

The mon1-ccz1 gef activates the rab7 gtpase ypt7 via a longin-fold-rab interface and association with pi3p-positive membranes
gan: Cabrera, M, et al.
Cyhoeddwyd: (2014)

The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes.
gan: Cabrera, M, et al.
Cyhoeddwyd: (2014)

Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells.
gan: Bo Xiong, et al.
Cyhoeddwyd: (2012-01-01)

Closing the gap : GEF experiences in global energy efficiency /
gan: Yang, Ming 1956-, author
Cyhoeddwyd: (♭201)

The RabGEF ALS2 is a hypoxia inducible target associated with the acquisition of aggressive traits in tumor cells
gan: Solange Rivas, et al.
Cyhoeddwyd: (2020-12-01)

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
Cyhoeddwyd: (2005-04-01)

Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration.
gan: Passley Hargrove-Grimes, et al.
Cyhoeddwyd: (2020-12-01)

融合蛋白TAT-RabGEF1原核表达载体的构建及蛋白表达
gan: 方虹仪, et al.
Cyhoeddwyd: (2018-01-01)

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
gan: Brent Wilkinson, et al.
Cyhoeddwyd: (2017-07-01)

Auto-regulation of Rab5 GEF activity in Rabex5 by allosteric structural changes, catalytic core dynamics and ubiquitin binding
gan: Janelle Lauer, et al.
Cyhoeddwyd: (2019-11-01)

Analysis of rab GTPases.
gan: Langemeyer, L, et al.
Cyhoeddwyd: (2012)

Analysis of Rab GTPases
gan: Langemeyer, L, et al.
Cyhoeddwyd: (2012)

GEF operational programs /
gan: United States Global Environment Facility
Cyhoeddwyd: (1997)

Rab GTPase function in Golgi trafficking.
gan: Barr, F
Cyhoeddwyd: (2009)

The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy
gan: Carroll, B, et al.
Cyhoeddwyd: (2013)

The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts
gan: Naomi Matsumoto, et al.
Cyhoeddwyd: (2022-05-01)

Stratum, a Homolog of the Human GEF Mss4, Partnered with Rab8, Controls the Basal Restriction of Basement Membrane Proteins in Epithelial Cells
gan: Olivier Devergne, et al.
Cyhoeddwyd: (2017-02-01)

Extracellular superoxide dismutase regulates the expression of small gtpase regulatory proteins GEFs, GAPs, and GDI.
gan: Mikko O Laukkanen, et al.
Cyhoeddwyd: (2015-01-01)

The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles.
gan: Lachmann, J, et al.
Cyhoeddwyd: (2012)

Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment.
gan: Zenner, H, et al.
Cyhoeddwyd: (2011)

Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development.
gan: Theresa A Reimels, et al.
Cyhoeddwyd: (2024-01-01)

Expanding the regulatory repertoire of GEFs.
gan: Richard Robinson
Cyhoeddwyd: (2013-09-01)

Biochemical and structural characterization of Rab3GAP reveals insights into Rab18 nucleotide exchange activity
gan: Gage M. J. Fairlie, et al.
Cyhoeddwyd: (2025-01-01)

Insulin and AMPK regulate FA translocase/CD36 plasma membrane recruitment in cardiomyocytes via Rab GAP AS160 and Rab8a Rab GTPase
gan: Dmitri Samovski, et al.
Cyhoeddwyd: (2012-04-01)

Genetic analysis of GEFs and GDIs in rice reveals the roles of OsGEF5, OsGDI1, and OsGEF3 in the regulation of grain size and plant height
gan: Munsif Ali Shad, et al.
Cyhoeddwyd: (2023-04-01)

RabGEF1/Rabex-5 Regulates TrkA-Mediated Neurite Outgrowth and NMDA-Induced Signaling Activation in NGF-Differentiated PC12 Cells.
gan: See-Ying Tam, et al.
Cyhoeddwyd: (2015-01-01)

Stress-dependent inhibition of polarized cell growth through unbalancing the GEF/GAP regulation of Cdc42
gan: Clàudia Salat-Canela, et al.
Cyhoeddwyd: (2021-11-01)

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.
gan: Alexandra Rasnitsyn, et al.
Cyhoeddwyd: (2017-01-01)

Review series: Rab GTPases and membrane identity: causal or inconsequential?
gan: Barr, F
Cyhoeddwyd: (2013)

Genetics of Febrile Seizures and Epilepsy (GEFS+)
gan: J Gordon Millichap
Cyhoeddwyd: (2008-04-01)

Modelling the widths of fission observables in GEF
gan: Schmidt K.-H., et al.
Cyhoeddwyd: (2013-03-01)

Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation
gan: Langemeyer, L, et al.
Cyhoeddwyd: (2014)

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
gan: Koji Yamano, et al.
Cyhoeddwyd: (2014-02-01)

P245: Oldest reported patients with RAB18 deficiency due to RAB3GAP1 gene mutations
gan: Dmitriy Niyazov, et al.
Cyhoeddwyd: (2024-01-01)

A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production
gan: Vinod Udayar, et al.
Cyhoeddwyd: (2013-12-01)