Rab GEFs and GAPs.

Rab GEFs and GAPs.

Rabs are GTP-binding proteins with conserved functions in membrane trafficking. They are regulated by a diverse group of structurally unrelated GDP-GTP exchange factors (GEFs), and a family of GTP-hydrolysis activating proteins (GAPs) containing the conserved TBC domain. Recent structural and cell b...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Barr, F, Lambright, D
Format:	Journal article
Sprog:	English
Udgivet:	2010

Lignende værker

Rab regulation by GEFs and GAPs during membrane traffic
af: Lamber, E, et al.
Udgivet: (2019)

Rab18 and a Rab18 GEF complex are required for normal ER structure.
af: Gerondopoulos, A, et al.
Udgivet: (2014)

RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
af: Nottingham, R, et al.
Udgivet: (2011)

Planar cell polarity effector proteins inturned and fuzzy form a Rab23 GEF complex
af: Gerondopoulos, A, et al.
Udgivet: (2019)

RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36.
af: Nottingham, R, et al.
Udgivet: (2012)

The mon1-ccz1 gef activates the rab7 gtpase ypt7 via a longin-fold-rab interface and association with pi3p-positive membranes
af: Cabrera, M, et al.
Udgivet: (2014)

The Mon1-Ccz1 GEF activates the Rab7 GTPase Ypt7 via a longin-fold-Rab interface and association with PI3P-positive membranes.
af: Cabrera, M, et al.
Udgivet: (2014)

Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells.
af: Bo Xiong, et al.
Udgivet: (2012-01-01)

Closing the gap : GEF experiences in global energy efficiency /
af: Yang, Ming 1956-, author
Udgivet: (♭201)

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
Udgivet: (2005-04-01)

融合蛋白TAT-RabGEF1原核表达载体的构建及蛋白表达
af: 方虹仪, et al.
Udgivet: (2018-01-01)

Auto-regulation of Rab5 GEF activity in Rabex5 by allosteric structural changes, catalytic core dynamics and ubiquitin binding
af: Janelle Lauer, et al.
Udgivet: (2019-11-01)

Analysis of rab GTPases.
af: Langemeyer, L, et al.
Udgivet: (2012)

Analysis of Rab GTPases
af: Langemeyer, L, et al.
Udgivet: (2012)

GEF operational programs /
af: United States Global Environment Facility
Udgivet: (1997)

The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts
af: Naomi Matsumoto, et al.
Udgivet: (2022-05-01)

Rab GTPase function in Golgi trafficking.
af: Barr, F
Udgivet: (2009)

Extracellular superoxide dismutase regulates the expression of small gtpase regulatory proteins GEFs, GAPs, and GDI.
af: Mikko O Laukkanen, et al.
Udgivet: (2015-01-01)

The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy
af: Carroll, B, et al.
Udgivet: (2013)

Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development.
af: Theresa A Reimels, et al.
Udgivet: (2024-01-01)

Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment.
af: Zenner, H, et al.
Udgivet: (2011)

The Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuoles.
af: Lachmann, J, et al.
Udgivet: (2012)

Genetic analysis of GEFs and GDIs in rice reveals the roles of OsGEF5, OsGDI1, and OsGEF3 in the regulation of grain size and plant height
af: Munsif Ali Shad, et al.
Udgivet: (2023-04-01)

Biochemical and structural characterization of Rab3GAP reveals insights into Rab18 nucleotide exchange activity
af: Gage M. J. Fairlie, et al.
Udgivet: (2025-01-01)

Genetics of Febrile Seizures and Epilepsy (GEFS+)
af: J Gordon Millichap
Udgivet: (2008-04-01)

Modelling the widths of fission observables in GEF
af: Schmidt K.-H., et al.
Udgivet: (2013-03-01)

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25.
af: Alexandra Rasnitsyn, et al.
Udgivet: (2017-01-01)

Review series: Rab GTPases and membrane identity: causal or inconsequential?
af: Barr, F
Udgivet: (2013)

TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization
af: Leo TH Tang, et al.
Udgivet: (2019-01-01)

Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation
af: Langemeyer, L, et al.
Udgivet: (2014)

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy
af: Koji Yamano, et al.
Udgivet: (2014-02-01)

P245: Oldest reported patients with RAB18 deficiency due to RAB3GAP1 gene mutations
af: Dmitriy Niyazov, et al.
Udgivet: (2024-01-01)

A Paired RNAi and RabGAP Overexpression Screen Identifies Rab11 as a Regulator of β-Amyloid Production
af: Vinod Udayar, et al.
Udgivet: (2013-12-01)

Anthraquinones as Inhibitors of SOS RAS-GEF Activity
af: Alberto Fernández-Medarde, et al.
Udgivet: (2021-07-01)

The Vav GEF Family: An Evolutionary and Functional Perspective
af: Sonia Rodríguez-Fdez, et al.
Udgivet: (2019-05-01)

Hydrographic data from the GEF Patagonia cruises
af: M. Charo, et al.
Udgivet: (2014-06-01)

General description of fission observables: The GEF code
af: Schmidt Karl-Heinz, et al.
Udgivet: (2017-01-01)

Genetic epilepsy with febrile seizures plus (GEFS+)
af: A. A. Sharkov
Udgivet: (2020-07-01)

The identification of protein domains that mediate functional interactions between Rab-GTPases and RabGAPs using 3D protein modeling
af: Davie JJ, et al.
Udgivet: (2017-04-01)

Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation
af: Lars Langemeyer, et al.
Udgivet: (2014-02-01)