GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis

Gasdermins are a family of structurally related proteins originally described for their role in pyroptosis. Gasdermin B (GSDMB) is currently the least studied, and while its association with genetic susceptibility to chronic mucosal inflammatory disorders is well established, little is known about i...

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Bibliographic Details
Main Authors: Rana, N, Privitera, G, Kondolf, HC, Bulek, K, Lechuga, S, De Salvo, C, Corridoni, D, Antanaviciute, A, Maywald, RL, Hurtado, AM, Zhao, J, Huang, EH, Li, X, Chan, ER, Simmons, A, Bamias, G, Abbott, DW, Heaney, JD, Ivanov, AI, Pizarro, TT
Format: Journal article
Language:English
Published: Cell Press 2022