Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity.
Plasmodium falciparum is the major cause of malaria globally and is transmitted by mosquitoes. During parasitic development, P. falciparum-infected erythrocytes (P. falciparum-IEs) express multiple polymorphic proteins known as variant surface antigens (VSAs), including the P. falciparum erythrocyte...
المؤلفون الرئيسيون: | Chan, J, Howell, K, Reiling, L, Ataide, R, Mackintosh, C, Fowkes, F, Petter, M, Chesson, J, Langer, C, Warimwe, G, Duffy, M, Rogerson, S, Bull, P, Cowman, A, Marsh, K, Beeson, J |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2012
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مواد مشابهة
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PFEMP1 IS THE MAJOR TARGET OF ANTIBODIES TO THE SURFACE OF PLASMODIUM FALCIPARUM-INFECTED ERYTHROCYTES THAT ARE ASSOCIATED WITH PROTECTION FROM MALARIA
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QUANTIFYING THE IMPORTANCE OF PFEMP1 AND OTHER ANTIGENS EXPRESSED ON THE SURFACE OF PLASMODIUM FALCIPARUM-INFECTED ERYTHROCYTES AS TARGETS OF PROTECTIVE ANTIBODIES AGAINST MALARIA
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PfEMP1 is the major target of antibodies to the surface of P-falciparum-infected erythrocytes that are associated with protection from malaria.
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A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies
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