Discovery of a CD10 negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Human lymphopoiesis is a dynamic life-long process that starts in utero 6 weeks post-conception. Fetal B-lymphopoiesis remains poorly defined and yet is key to understanding leukemia initiation in early life. Here, we provide a comprehensive analysis of the human fetal B-cell developmental hierarchy...

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Bibliographic Details
Main Authors:	O'Byrne, S, Elliott, N, Rice, S, Buck, G, Fordham, N, Garnett, C, Godfrey, L, Crump, N, Wright, G, Inglott, S, Hua, P, Psaila, B, Povinelli, B, Knapp, D, Agraz-Doblas, A, Bueno, C, Varela, I, Bennett, P, Koohy, H, Watt, S, Karadimitris, A, Mead, A, Ancliff, P, Vyas, P, Menendez, P, Milne, T, Roberts, I, Roy, A
Format:	Journal article
Language:	English
Published:	American Society of Hematology 2019

Discovery of a CD10 negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

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