The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene.

We have investigated the developmental and tissue specific expression of the human embryonic zeta-globin gene in transgenic mice. A construct containing 550 bp of zeta-globin 5' flanking region, fused to a beta-galactosidase (lacZ) reporter gene and linked to the locus control region (LCR)-like...

ver descrição completa

Detalhes bibliográficos
Main Authors: Pondel, MD, Proudfoot, N, Whitelaw, C, Whitelaw, E
Formato: Journal article
Idioma:English
Publicado em: 1992