The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene.
We have investigated the developmental and tissue specific expression of the human embryonic zeta-globin gene in transgenic mice. A construct containing 550 bp of zeta-globin 5' flanking region, fused to a beta-galactosidase (lacZ) reporter gene and linked to the locus control region (LCR)-like...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
1992
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