Agile CD22 nanoclusters run rings around fenced BCR

B lymphocytes are key players in host defence, but also autoimmune diseases. Their survival depends upon tonic signals transduced by surface immunoglobulin (BCR) and the process leading to antibody secretion is initiated by interaction of BCR with a cognate antigen. CD22 limits signalling of the BCR...

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Bibliographic Details
Main Authors: Depoil, D, Dustin, M
Format: Journal article
Language:English
Published: EMBO Press 2016