Elevated CD54 expression renders CD4+ T cells susceptible to NK cell-mediated killing.
A decreased number of CD4+ T cells is a major feature of HIV infection. Here we detected high CD54 expression on CD4+ T cells in HIV-infected individuals, and demonstrate that upregulated CD54 is associated with disease progression in individuals infected with HIV. We also show that CD54 expression...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Oxford University Press
2019
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