Elevated CD54 expression renders CD4+ T cells susceptible to NK cell-mediated killing.
A decreased number of CD4+ T cells is a major feature of HIV infection. Here we detected high CD54 expression on CD4+ T cells in HIV-infected individuals, and demonstrate that upregulated CD54 is associated with disease progression in individuals infected with HIV. We also show that CD54 expression...
প্রধান লেখক: | , , , , , , , , , , , |
---|---|
বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
Oxford University Press
2019
|