A positive feedback loop drives centrosome maturation in flies

Centrosomes are formed when mother centrioles recruit pericentriolar material (PCM) around themselves. The PCM expands dramatically as cells prepare to enter mitosis (a process termed centrosome maturation), but it is unclear how this expansion is achieved. In flies, Spd-2 and Cnn form an extensive...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Alvarez Rodrigo, I, Conduit, P, Baumbach, J, Novak, Z, Aydogan, M, Wainman, A, Raff, J
Formaat: Journal article
Gepubliceerd in: ColdSpring Habor Laboratory 2018