A positive feedback loop drives centrosome maturation in flies

Centrosomes are formed when mother centrioles recruit pericentriolar material (PCM) around themselves. The PCM expands dramatically as cells prepare to enter mitosis (a process termed centrosome maturation), but it is unclear how this expansion is achieved. In flies, Spd-2 and Cnn form an extensive...

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Bibliographic Details
Main Authors: Alvarez Rodrigo, I, Conduit, P, Baumbach, J, Novak, Z, Aydogan, M, Wainman, A, Raff, J
Format: Journal article
Published: ColdSpring Habor Laboratory 2018