A positive feedback loop drives centrosome maturation in flies
Centrosomes are formed when mother centrioles recruit pericentriolar material (PCM) around themselves. The PCM expands dramatically as cells prepare to enter mitosis (a process termed centrosome maturation), but it is unclear how this expansion is achieved. In flies, Spd-2 and Cnn form an extensive...
Main Authors: | Alvarez Rodrigo, I, Conduit, P, Baumbach, J, Novak, Z, Aydogan, M, Wainman, A, Raff, J |
---|---|
Format: | Journal article |
Published: |
ColdSpring Habor Laboratory
2018
|
Similar Items
-
Evidence that a positive feedback loop drives centrosome maturation in fly embryos
by: Alvarez-Rodrigo, I, et al.
Published: (2019) -
The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation.
by: Conduit, P, et al.
Published: (2014) -
Centrosome function and assembly in animal cells
by: Conduit, P, et al.
Published: (2015) -
Structural basis for mitotic centrosome assembly in flies
by: Feng, Z, et al.
Published: (2017) -
Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts.
by: Conduit, P, et al.
Published: (2010)