Separation of monoclonal antibody alemtuzumab monomer and dimers using ultrafiltration.

This article examines the feasibility of using ultrafiltration to separate the monomer of the monoclonal antibody alemtuzumab (Campath or Campath-1H) from a mixture of dimer and higher-order oligomers (collectively called "dimers" here). Using parameter scanning ultrafiltration, we initial...

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Bibliographic Details
Main Authors: Wan, Y, Vasan, S, Ghosh, R, Hale, G, Cui, Z
Format: Journal article
Language:English
Published: 2005