Development of bisulfite-free DNA methylation sequencing methods and their application to cell-free DNA for cancer detection

Development of bisulfite-free DNA methylation sequencing methods and their application to cell-free DNA for cancer detection

<p>5-Methylcytosine (5mC) is the most abundant epigenetic mark in DNA regulating gene expression and influencing crucial cellular processes. Aberrant DNA methylation is involved in pathogenesis of human malignancies. Detection of cancer-specific methylation patterns in cell-free DNA (cfDNA) is...

Bibliografiset tiedot
Päätekijä:	Siejka-Zielinska, P
Muut tekijät:	Kriaucionis, S
Aineistotyyppi:	Opinnäyte
Kieli:	English
Julkaistu:	2020
Aiheet:	Cancer Epigenetics Bioinformatics Liquid biopsy

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