Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol

Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol

Show other versions (1)

We report the outcome for children and young people with Down syndrome-associated acute lymphoblastic leukaemia (DS-ALL) treated on a contemporary protocol. Compared with non-DS ALL, patients with DS-ALL had an inferior event-free survival (65·6% vs. 87·7% at 5 years; P < 0·00005) and overall...

書目詳細資料
Main Authors:	Patrick, K, Wade, R, Goulden, N, Rowntree, C, Hough, R, Moorman, A, Mitchell, C, Vora, A
格式:	Journal article
語言:	English
出版:	Blackwell Publishing Ltd 2014

相似書籍

Outcome of Down syndrome associated acute lymphoblastic leukaemia treated on a contemporary protocol.
由: Patrick, K, et al.
出版: (2014)

Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003
由: Patrick, K, et al.
出版: (2014)

Outcome for children and young people with Early T-cell precursor acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.
由: Patrick, K, et al.
出版: (2014)

Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.
由: Vora, A, et al.
出版: (2014)

Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): A randomised controlled trial
由: Vora, A, et al.
出版: (2014)

Incidence and outcome of pancreatitis in children and young adults with acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003
由: Samarasinghe, S, et al.
出版: (2013)

Incidence and outcome of pancreatitis in children and young adults with acute lymphoblastic leukaemia treated on a contemporary protocol, UKALL 2003.
由: Samarasinghe, S, et al.
出版: (2013)

Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial.
由: Vora, A, et al.
出版: (2013)

Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial
由: Vora, A, et al.
出版: (2013)

Incidence and Outcome of Osteonecrosis in Children and Young Adults with Acute Lymphoblastic Leukaemia Treated on a Dexamethasone Containing Protocol: Results of the Medical Research Council UK Trial ALL 2003
由: Vora, A, et al.
出版: (2008)

Profile of Steroid Toxicity During Maintenance Treatment in Teenage and Young Adult (TYA) Patients with Acute Lymphoblastic Leukaemia (ALL)
由: Tomlins, J, et al.
出版: (2012)

Genotype-specific MRD interpretation improves stratification in paediatric acute lymphoblastic leukaemia
由: O'Connor, D, et al.
出版: (2017)

Down Syndrome is a significant risk factor for infectious deaths in childhood acute lymphoblastic leukaemia: a retrospective analysis of the infectious deaths on UKALL 2003
由: O'Connor, D, et al.
出版: (2014)

Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MRD) clearance in childhood acute lymphoblastic leukaemia (ALL)
由: Moorman, A, et al.
出版: (2007)

Cytogenetic-specific heterogeneity in the kinetics of minimal residual disease (MIRD) clearance in childhood lymphoblastic leukaemia (ALL)
由: Moorman, A, et al.
出版: (2008)

UKALL 2003, A Randomised Trial Investigating Treatment Intensification for Children and Young Adults with Minimal Residual Disease Defined High Risk Acute Lymphoblastic Leukaema
由: Vora, A, et al.
出版: (2012)

Improved Outcome for Children and Young Adults with T-Cell Acute Lymphoblastic Leukaemia (ALL): Results of the United Kingdom Medical Research Council (MRC) Trial UKALL 2003
由: Vora, A, et al.
出版: (2008)

Efficacy and Toxicity of Pegylated Asparaginase in the Treatment of Children and Young Adults with Acute Lymphoblastic Leukaemia: Results of the United Kingdom Medical Research Council (MRC) Trial UKALL 2003
由: Vora, A, et al.
出版: (2008)

Characteristics and outcome of children and young adults with Early T-Precursor (ETP) ALL treated on UKALL 2003
由: Patrick, K, et al.
出版: (2013)

Prospective evaluation of quality of life in children treated in UKALL 2003 for Acute Lymphoblastic Leukaemia (ALL): A cohort study
由: Eiser, C, et al.
出版: (2017)

Temporal changes in the incidence and pattern of central nervous system relapses in children with acute lymphoblastic leukaemia treated on four consecutive Medical Research Council trials, 1985-2001.
由: Krishnan, S, et al.
出版: (2010)

Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics
由: Moorman, A, et al.
出版: (2012)

PROSPECTIVE EVALUATION OF QUALITY OF LIFE (QOL) IN CHILDREN TREATED IN UKALL 2003 FOR ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL): A COHORT STUDY
由: Eiser, C, et al.
出版: (2012)

UKALL 2003, A Randomised Trial Investigating Treatment Reduction for Children and Young Adults with Minimal Residual Disease Defined Low Risk Acute Lymphoblastic Leukaemia
由: Vora, A, et al.
出版: (2010)

UKALL 2003, A Randomised Trial Investigating Treatment Reduction for Children and Young Adults with Minimal Residual Disease Defined Low Risk Acute Lymphoblastic Leukaemia
由: Vora, A, et al.
出版: (2010)

UKALL 2003, A Randomised Trial Investigating Treatment Reduction for Children and Young Adults with Minimal Residual Disease Defined Low Risk Acute Lymphoblastic Leukaemia
由: Vora, A, et al.
出版: (2010)

Three distinct subgroups of hypodiploidy in acute lymphoblastic leukaemia.
由: Harrison, C, et al.
出版: (2004)

Post-Remission MRD Kinetics in Children with Acute Lymphoblastic Leukaemia Receiving Augmented BFM Consolidation Compared with Other Regimens Results of the Medical Research Council Trial UKALL2003.
由: Cutting, R, et al.
出版: (2008)

Intraocular relapse of childhood acute lymphoblastic leukaemia.
由: Somervaille, T, et al.
出版: (2003)

Secondary acute myeloid leukaemia in children treated for acute lymphoblastic leukaemia.
由: Eden, O, et al.
出版: (1998)

Post-remission MRD kinetics in children with acute lymphoblastic leukaemia receiving augmented BFM consolidation compared with other regimens: update of results of the Medical Research Council Trial UKALL2003
由: Cutting, R, et al.
出版: (2009)

Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial.
由: Jenkinson, S, et al.
出版: (2013)

Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.
由: Lennard, L, et al.
出版: (2013)

Treatment of infants with lymphoblastic leukaemia: results of the UK Infant Protocols 1987-1999.
由: Chessells, J, et al.
出版: (2002)

Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia.
由: O'Connor, D, et al.
出版: (2017)

The clinical pharmacology of thioguanine vs. mercaptopurine in ALL97, a randomized trial for the treatment of childhood lymphoblastic leukaemia
由: Lennard, L, et al.
出版: (2008)

Down's syndrome and acute lymphoblastic leukaemia: clinical features and response to treatment.
由: Chessells, J, et al.
出版: (2001)

Late relapsing childhood acute lymphoblastic leukaemia.
由: Frost, L, et al.
出版: (1998)

Infection-related mortality in children with acute lymphoblastic leukemia: an analysis of infectious deaths on UKALL2003.
由: O'Connor, D, et al.
出版: (2014)

Late relapsing childhood lymphoblastic leukaemia.
由: Frost, L, et al.
出版: (1997)