Synthesis of novel pyridine-carboxylates as small-molecule inhibitors of human aspartate/asparagine-β-hydroxylase

The human 2-oxoglutarate (2OG)-dependent oxygenase aspartate/asparagine-β-hydroxylase (AspH) is a potential medicinal chemistry target for anti-cancer therapy. AspH is overexpressed on the cell surface of invasive cancer cells and accepts epidermal growth factor-like domain (EGFDs) substra...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Brewitz, L, Tumber, A, Thalhammer, A, Salah, E, Christensen, KE, Schofield, C
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: Wiley 2020