Structural insights into the function of ZRANB3 in replication stress response

Strategies to resolve replication blocks are critical for the maintenance of genome stability. Among the factors implicated in the replication stress response is the ATP-dependent endonuclease ZRANB3. Here, we present the structure of the ZRANB3 HNH (His-Asn-His) endonuclease domain and provide a de...

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Bibliographic Details
Main Authors: Sebesta, M, Cooper, C, Ariza, A, Carnie, C, Ahel, D
Format: Journal article
Language:English
Published: Springer Nature 2017