The structure of a LAIR1-containing human antibody reveals a novel mechanism of antigen recognition

Antibodies are critical components of the human adaptive immune system, providing versatile scaffolds to display diverse antigen-binding surfaces. Nevertheless, most antibodies have similar architectures, with the variable immunoglobulin domains of the heavy and light chain each providing three hype...

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Bibliographic Details
Main Authors: Hsieh, F, Higgins, M
Format: Journal article
Language:English
Published: eLife Sciences Publications 2017