Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia.

Hypertriglyceridemia and impaired fibrinolytic function are linked to coronary heart disease and other atherothrombotic disorders. Triglyceride-rich lipoproteins may attenuate fibrinolysis by increasing the plasma levels of plasminogen activator inhibitor-1 (PAI-1). Furthermore, a common 4/5 guanosi...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Eriksson, P, Nilsson, L, Karpe, F, Hamsten, A
स्वरूप: Journal article
भाषा:English
प्रकाशित: 1998

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