Congenital nephrotic syndrome in mice lacking CD2-associated protein.
CD2-associated protein (CD2AP) is an 80-kilodalton protein that is critical for stabilizing contacts between T cells and antigen-presenting cells. In CD2AP-deficient mice, immune function was compromised, but the mice died at 6 to 7 weeks of age from renal failure. In the kidney, CD2AP was expressed...
| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
1999
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