Analysis of the human alpha-globin gene cluster in transgenic mice.
A 350-bp segment of DNA associated with an erythroid-specific DNase I-hypersensitive site (HS-40), upstream of the alpha-globin gene cluster, has been identified as the major tissue-specific regulator of the alpha-globin genes. However, this element does not direct copy number-dependent or developme...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1993
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