IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal tract that is caused in part by a dysregulated immune response to the intestinal flora. The common interleukin (IL)-12/IL-23p40 subunit is thought to be critical for the pathogenesis of IBD. We have analyzed...

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Bibliographic Details
Main Authors: Kullberg, M, Jankovic, D, Feng, C, Hue, S, Gorelick, P, McKenzie, B, Cua, D, Powrie, F, Cheever, A, Maloy, K, Sher, A
Format: Journal article
Language:English
Published: 2006