The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells

The only currently available approach to early efficacy testing of tuberculosis (TB) vaccine candidates is in vivo preclinical challenge models. These typically include mice, guinea pigs and non-human primates (NHPs), which must be exposed to virulent M.tb in a ‘challenge’ experiment following vacci...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Tanner, R, Hoogkamer, E, Bitencourt, J, White, A, Boot, C, Sombroek, CC, Harris, SA, O'Shea, MK, Wright, D, Wittenberg, R, Sarfas, C, Satti, I, Verreck, FAW, Sharpe, SA, Fletcher, HA, McShane, H
Format:	Journal article
Sprog:	English
Udgivet:	F1000Research 2021

Lignende værker

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates
af: Tanner, R, et al.
Udgivet: (2021)

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates
af: Rachel Tanner, et al.
Udgivet: (2021-01-01)

A mycobacterial growth inhibition assay (MGIA) for bovine TB vaccine development
af: Pepponi, I, et al.
Udgivet: (2017)

The cross-species mycobacterial growth inhibition assay (MGIA) project 2010-2014
af: Brennan, M, et al.
Udgivet: (2017)

Tools for assessing the protective efficacy of TB vaccines in humans: in vitro mycobacterial growth inhibition predicts outcome of in vivo mycobacterial infection
af: Tanner, R, et al.
Udgivet: (2020)

Assessment of the reproducibility and inter-site transferability of the murine direct splenocyte mycobacterial growth inhibition assay (MGIA)
af: Tanner, R, et al.
Udgivet: (2021)

Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosis complex strains
af: Painter, H, et al.
Udgivet: (2024)

Development of a non-human primate BCG infection model for the evaluation of candidate tuberculosis vaccines
af: Harris, S, et al.
Udgivet: (2017)

In vitro mycobacterial growth inhibition assays: A tool for the assessment of protective immunity and evaluation of tuberculosis vaccine efficacy
af: Mcshane, H, et al.
Udgivet: (2017)

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb).
af: Marsay, L, et al.
Udgivet: (2013)

Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates
af: Alvarez, MPP, et al.
Udgivet: (2024)

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb)
af: Marsay, L, et al.
Udgivet: (2013)

Distinct transcriptional and anti-mycobacterial profiles of peripheral blood monocytes dependent on the ratio of monocytes: lymphocytes
af: Naranbhai, V, et al.
Udgivet: (2015)

Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection
af: O'Shea, M, et al.
Udgivet: (2018)

A review of clinical models for the evaluation of human TB vaccines.
af: O'Shea, M, et al.
Udgivet: (2016)

Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates
af: Marco Polo Peralta Alvarez, et al.
Udgivet: (2024-05-01)

Evaluation of immune profiles associated with control of mycobacterial growth in systemic lupus erythematosus (SLE) patients
af: Ongarj, J, et al.
Udgivet: (2024)

Development of mycobacterial growth inhibition assays for the early evaluation and gating of novel TB vaccine candidates
af: Tanner, R
Udgivet: (2015)

The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays
af: Tanner, R, et al.
Udgivet: (2017)

Gene expression and cytokine profile correlate with mycobacterial growth in a human BCG challenge model
af: Matsumiya, M, et al.
Udgivet: (2014)

Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery.
af: Meyer, J, et al.
Udgivet: (2013)

Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes
af: Vivek Naranbhai, et al.
Udgivet: (2015-11-01)

Induction of functional specific antibodies, IgG-secreting plasmablasts and memory B cells following BCG vaccination
af: Bitencourt, J, et al.
Udgivet: (2021)

Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery
af: Meyer, J, et al.
Udgivet: (2013)

MTBVAC induces superior antibody titers and IgG avidity compared to BCG vaccination in non-human primates
af: Peralta-Álvarez, MP, et al.
Udgivet: (2024)

Cytomegalovirus infection is a risk factor for TB disease in infants
af: Müller, J, et al.
Udgivet: (2019)

The characterisation of mycobacterial control profiles and underlying immune signatures in patients with latent tuberculosis infection and active disease
af: O'Shea, M
Udgivet: (2016)

Glycomimetic inhibitors of mycobacterial glycosyltransferases: targeting the TB cell wall.
af: Lucas, R, et al.
Udgivet: (2008)

Non-TB mycobacterial infections in patients with non-CF bronchiectasis
af: M Mirsaeidi, et al.
Udgivet: (2015-01-01)

Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin
af: McNeill, E, et al.
Udgivet: (2018)

Quantitative Rapid Test for Detection and Monitoring of Active Pulmonary Tuberculosis in Nonhuman Primates
af: Zijie Zhou, et al.
Udgivet: (2021-12-01)

Human Hookworm Infection Enhances Mycobacterial Growth Inhibition and Associates With Reduced Risk of Tuberculosis Infection
af: Matthew K. O'Shea, et al.
Udgivet: (2018-12-01)

Human hookworm infection enhances mycobacterial growth inhibition and associates with reduced risk of tuberculosis infection
af: O'Shea, M, et al.
Udgivet: (2018)

Host Immune-Metabolic Adaptations Upon Mycobacterial Infections and Associated Co-Morbidities
af: Alba Llibre, et al.
Udgivet: (2021-09-01)

Development and application of the direct mycobacterial growth inhibition assay: a systematic review
af: Painter, H, et al.
Udgivet: (2024)

Using aerosol Bacille Calmette-Guérin in non-human primates to model the immune response to Mycobacterium Tuberculosis: a translational bridge between preclinical models and clinical trials
af: Hoogkamer, E
Udgivet: (2022)

Development and application of the direct mycobacterial growth inhibition assay: a systematic review
af: Hannah Painter, et al.
Udgivet: (2024-02-01)

Phase I trial evaluating the safety and immunogenicity of candidate TB vaccine MVA85A, delivered by aerosol to healthy M.tb-infected adults
af: Riste, M, et al.
Udgivet: (2021)

Risk factors for atypical mycobacterial disease in patients with smear positive pulmonary TB
af: Hany Shaarawy, et al.
Udgivet: (2014-07-01)

Evaluating aerosol administration of a candidate TB vaccine MVA85A
af: Thomas, Z, et al.
Udgivet: (2014)