Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes.

Initial results from sequencing studies suggest that there are relatively few low-frequency (<5%) variants associated with large effects on common phenotypes. We performed low-pass whole-genome sequencing in 680 individuals from the InCHIANTI study to test two primary hypotheses: (i) that seq...

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Bibliografiska uppgifter
Huvudupphovsmän:	Wood, A, Tuke, M, Nalls, M, Hernandez, D, Gibbs, JR, Lin, H, Xu, C, Li, Q, Shen, J, Jun, G, Almeida, M, Tanaka, T, Perry, JR, Gaulton, K, Rivas, M, Pearson, R, Curran, J, Johnson, M, Göring, H, Duggirala, R, Blangero, J, Mccarthy, M, Bandinelli, S, Murray, A, Weedon, M
Materialtyp:	Journal article
Språk:	English
Publicerad:	2014

Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes.

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