A hybrid approach to multi-scale modelling of cancer
In this paper, we review multi-scale models of solid tumour growth and discuss a middle-out framework that tracks individual cells. By focusing on the cellular dynamics of a healthy colorectal crypt and its invasion by mutant, cancerous cells, we compare a cell-centre, a cell-vertex and a continuum...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Royal Society Publishing
2010
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