A hybrid approach to multi-scale modelling of cancer
In this paper, we review multi-scale models of solid tumour growth and discuss a middle-out framework that tracks individual cells. By focusing on the cellular dynamics of a healthy colorectal crypt and its invasion by mutant, cancerous cells, we compare a cell-centre, a cell-vertex and a continuum...
Автори: | Osborne, J, Walter, A, Kershaw, S, Mirams, G, Fletcher, A, Pathmanathan, P, Gavaghan, D, Jensen, O, Maini, P, Byrne, H |
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Формат: | Journal article |
Опубліковано: |
Royal Society Publishing
2010
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