Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain.
The ubiquitin-pathway associated (UBA) domain is a 40-residue polyubiquitin-binding motif. The Schizosaccharomyces pombe protein Mud1 is an ortholog of the Saccharomyces cerevisiae DNA-damage response protein Ddi1 and binds to K48-linked polyubiquitin through its UBA domain. We have solved the cryst...
| Main Authors: | , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2005
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