Timing of CD8+ T cell responses in relation to commencement of capillary leakage in children with dengue.

Immune activation is a feature of dengue hemorrhagic fever (DHF) and CD8+ T cell responses in particular have been suggested as having a role in the vasculopathy that characterizes this disease. By phenotyping CD8+ T cells (CD38+/HLA-DR+, CD38+/Ki-67+, or HLA-DR+/Ki-67+) in serial blood samples from...

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Bibliographic Details
Main Authors: Dung, N, Duyen, H, Thuy, N, Ngoc, T, Chau, N, Hien, T, Rowland-Jones, S, Dong, T, Farrar, J, Wills, B, Simmons, C
Format: Journal article
Language:English
Published: 2010