Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Through major histocompatibility complex class Ia leader sequence-derived (VL9) peptide binding and CD94/NKG2 receptor engagement, human leucocyte antigen E (HLA-E) reports cellular health to NK cells. Previous studies demonstrated a strong bias for VL9 binding by HLA-E, a preference subsequently su...

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Egile Nagusiak: Walters, L, Harlos, K, Brackenridge, S, Rozbesky, D, Barrett, J, Jain, V, Walter, T, O'Callaghan, C, Borrow, P, Toebes, M, Hansen, S, Sacha, J, Abdulhaqq, S, Greene, J, Früh, K, Marshall, E, Picker, L, Jones, E, McMichael, A, Gillespie, G
Formatua: Journal article
Hizkuntza:English
Argitaratua: Springer Nature 2018

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