Plasticity of the TSG-6 HA-binding loop and mobility in the TSG-6-HA complex revealed by NMR and X-ray crystallography.

Tumour necrosis factor-stimulated gene-6 (TSG-6) is a glycosaminoglycan-binding protein expressed during inflammatory and inflammation-like processes. Previously NMR structures were calculated for the Link module of TSG-6 (Link_TSG6) in its free state and when bound to an octasaccharide of hyalurona...

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Bibliographic Details
Main Authors: Higman, V, Blundell, C, Mahoney, D, Redfield, C, Noble, M, Day, A
Format: Journal article
Language:English
Published: 2007