Identification and functional analysis of single nucleotide polymorphisms that affect human cancer

Aims: The p53 regulatory network is crucial in directing the suppression of cancer formation and mediating the response to commonly used cancer therapies. Functional genetic variants in the genes comprising this network could help identify individuals at greater risk for cancer and patients with poo...

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Bibliographic Details
Main Author: Grochola, LF
Other Authors: Bond, G
Format: Thesis
Language:English
Published: 2011
Subjects: